Email this article Experience of using the 1,5% Tetranyl U cream in patients with tinea corporis and tinea cruris
- Authors: Maximov I.S.1, Petukhova E.V.1
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Affiliations:
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- Issue: Vol 25, No 2 (2022)
- Pages: 151-158
- Section: DERMATOLOGY
- URL: https://journals.rcsi.science/1560-9588/article/view/109086
- DOI: https://doi.org/10.17816/dv109086
- ID: 109086
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Abstract
BACKGROUND: Over the past ten years, there has been a persistent increase in the resistance of dermatophytes to antifungal drugs. The development of new drugs and the evaluation of the effectiveness of medicines is a priority in mycology.
AIMS: Evaluation of the effectiveness and safety of using the cream containing Tetranyl U and 10% urea in the treatment of tinea corporis and tinea cruris.
MATERIALS AND METHODS: The study included 30 patients with a laboratory-confirmed diagnosis of tinea corporis and tinea cruris of mild to moderate severity. Patients were recommended to use the cream which was applied to the lesions 2 times a day for 3 weeks. The evaluation of the severity the course of mycosis and the effectiveness of the cream was carried out by calculating a 4-point PGA (Physician Global Assessment) before treatment and after 3 weeks of using the cream.
RESULTS: According to the results of the study, the clinical efficacy was 81.8%. Mycological response (negative direct microscopy + mycological culture) was achieved in 82.8% of patients.
CONCLUSION: The cream containing Tetranyl U showed good efficacy and tolerability in the treatment of tinea corporis and tinea cruris, which is confirmed by the results of clinical and microbiological studies.
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##article.viewOnOriginalSite##About the authors
Ivan S. Maximov
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Author for correspondence.
Email: maximov.is@mail.ru
ORCID iD: 0000-0003-2850-2910
Assistant
Russian Federation, MoscowEugenia V. Petukhova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: petuxova0304@gmail.com
ORCID iD: 0000-0002-9396-4874
Student
Russian Federation, MoscowReferences
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