Clinical and epidemiological characteristics of ebola at the present stage


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The disease being caused by the Ebola virus (Ebola virus disease - EVD, Ebola haemorrhagic fever) referred to the genus Ebolaviruses - is a viral haemorrhagic fever in human and other primates subjects. There is a reason to consider frugivorous bats - the inhabitants of the tropics as the natural reservoir of the virus. The transmission from person to person by airborne droplets has not been proved. Signs and symptoms of the disease usually begin during the period from two days to three weeks after infection with fever virus, from sore throat, muscle pains and headaches. Then there are affiliated vomiting, diarrhea, rash, disorder of the function of liver and kidneys. In many patients there are adhered the external and internal bleeding. The mortality rate in this disease varies between 25 and 90 percent, in average about 50 percent. The cause of the lethal outcome in most cases is toxic shock and/or hypovolemic dehydration shock, which occurs usually after six to sixteen days from the onset of the disease. Therapy is limited to a complex ofpathogenetic therapeutic measures, as there is no specific treatment. EVD vaccines are at the final stages of the delivery.

作者简介

V. Nikiforov

Russian National Research Medical University named after N.I. Pirogov

Email: v.v.nikiforov@gmail.com
доктор мед. наук, проф., зав. каф. инфекционных болезней и эпидемиологии ГБОУ ВПО РНИМУ им. Н.И. Пирогова Минздрава России, главный инфекционист ФМБА России, засл. врач Российской Федерации, эксперт ООН от Российской Федерации по расследованию предполагаемого применения химического и биологического оружия 1, Ostrovityanova str., Moscow, 117997, Russian Federation

M. Shakhmardanov

Russian National Research Medical University named after N.I. Pirogov

Email: mur2025@rambler.ru
доктор мед. наук, проф. каф. инфекционных болезней и эпидемиологии 1, Ostrovityanova str., Moscow, 117997, Russian Federation

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