IMMUNOLOGICAL PARAMETERSAND BLOOD LYMPHOCYTE ENZYME PROFILE IN BABIES WITH RECURRENT RESPIRATORY INFECTIONS


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Abstract

84 babies aged 1 to 3 years suffered from recurrent respiratory infections were studied. Cellular and humoral immunological parameters, phagocytic activity of neutrophils and activities of NAD- and NADP-dependent dehydrogenases in peripheral blood lymphocytes were estimated. Immunophenotypic changes found in blood lymphocytes included decreased IgA levels and a tendency of serum IgM to increase. An elevated level of circulating immune complexes was revealed in the blood serum. Decreased levels active neutrophils in the peripheral blood were detected. In the enzyme status of blood lymphocytes such changes as increased levels of synthetic processes and intense intracellular energy metabolism can be observed.

About the authors

L. M Kurtasova

State educational institution of higher professional education Krasnoyarsk State Medical University named after Professor V. F. Voino-Yasenetsky of the Ministry of Health care and Social Development of the Russian Federation

Email: aids@ktk.ru
д-р мед. наук, проф., каф. клинической иммунологии 1, Partizana Zheleznyaka St., Krasnoyarsk, Russian Federation, 660022

T. V. Lubnina

Treasury State Budjetary Institution of healthcare Krasnoyarsk Regional Centerfor the Prevention and Control of AIDS and other infectious diseases

врач-педиатр лечебноконсультативного отд-ния Красноярского краевого центра по профилактике и борьбе со СПИД и инфекционными заболеваниями. 45, Karla Marksa Str., Krasnoyarsk, Russian Federation

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