Regularities of changes in laboratory parameters in patients with A/H1N1 influenza pneumonia

Elena Nikolaevna Romanova; Романова Елена Николаевна; Ol'ga Mikhaylovna Serebryakova; Серебрякова Ольга Михайловна; Anatoliy Vasil'evich Govorin; Говорин Анатолий Васильевич; Andrey Petrovich Filev; Филев Андрей Петрович; E N Romanova; Romanova E N; O M Serebryakova; Serebryakova O M; A V Govorin; Govorin A V; A P Filev; Filev A P

doi:10.17816/EID40561

Regularities of changes in laboratory parameters in patients with A/H1N1 influenza pneumonia

Authors: Romanova E.N.¹, Serebryakova O.M.², Govorin A.V.¹, Filev A.P.¹, Romanova EN³, Serebryakova OM⁴, Govorin AV³, Filev AP³
Affiliations:
1. ГОУ ВПО Читинская государственная медицинская академия Минздравсоцразвития
2. МУЗ Городская клиническая больница № 1
3. Chita State Medical Academy, Ministry of Health and Social Development
4. Town Clinical Hospital One
Issue: Vol 16, No 4 (2011)
Pages: 23-27
Section: Articles
URL: https://journals.rcsi.science/1560-9529/article/view/40561
DOI: https://doi.org/10.17816/EID40561
ID: 40561

Cite item

Abstract

The medical records of 97 patients with A/H1N1 influenza pneumonia were analyzed. The important feature of the disease is a high risk of fatal outcomes, the direct cause of which is acute respiratory distress syndrome (ARDS). The most significant abnormalities of laboratory values were noted in this category of patients. In ARDS, leukopenia or normocytosis changed to leukocytosis, which is attributed to massive bacterial infection. These patients were also recorded to have immunodeficiency-induced lymphopenia and disseminated intravascular coagulation-induced thrombocytopenia. The marked elevation of transaminases mainly due to asparagine transaminase and the increase of creatine phosphokinase suggest that the most severe category of patients has rhabdomyolysis. Characteristic of this was a reactive rise of amylase. In ARDS, diminished renal functional capacity reflected the higher blood levels of creatinine and urea.

Keywords

community-acquired pneumonia, A/H1N1 influenza, acute lung injury, acute respiratory distress syndrome

References

Гельфанд Б. Р., Кассиль В. Л. Острый респираторный дистресс-синдром. - М., 2007.
Кассиль В. Л., Золотокрылина Е. С. Острый респираторный дистресс-синдром. - М., 2003.
Лапа С. А., Родина Н. Н., Скрипченко Е. М. и др. Эпидемиологическая ситуация по гриппу A/H1N1 в Забайкальском крае в 2009-2010 годах // Материалы Всероссийской науч.-практ. конф. с международным участием "Итоги эпидемии гриппа A/H1N1". Чита, 26-27 окт. 2010. - Чита, 2010. - С. 154-157.
Внебольничная пневмония у взрослых: Практ. рекомендации по диагностике, лечению и профилактике / Чучалин А. Г., Синопальниов А. И., Страчунский Л. С. и др. - М., 2009.
Чучалин А. Г. Грипп: уроки пандемии // Пульмонология. - 2010. - Прил.: Грипп A/H1N1: уроки пандемии. - С. 3-8.
Rise T. W., Wheeler A. P., Bernard G. R. et al. Comparison of SpO2/FiO2 ratio in patients with acute lung injury or ARDS // Chest. - 2007. - Vol. 132. - P. 410-417.

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Regularities of changes in laboratory parameters in patients with A/H1N1 influenza pneumonia

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