Synthesis and Study of Nanocomposites Based on Beta Zeolite and Magnetite for Targeted Drug Delivery
- Authors: Golubeva O.Y.1, Brazovskaya E.Y.1, Alikina Y.A.1,2, D’yachenko S.V.2, Zhernovoi A.I.2
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Affiliations:
- Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences
- St. Petersburg State Institute of Technology (Technical University)
- Issue: Vol 45, No 1 (2019)
- Pages: 66-73
- Section: Article
- URL: https://journals.rcsi.science/1087-6596/article/view/216999
- DOI: https://doi.org/10.1134/S1087659619010036
- ID: 216999
Cite item
Abstract
Magnetic nanocomposites based on Beta zeolites and magnetite nanoparticles modified with polydiallyldimethylammonium chloride are synthesized under hydrothermal conditions. Particles of an average size of 100–200 nm characterized with magnetic moments and a high sorption capacity towards the model drug, thiamine hydrochloride (vitamin B1), are obtained. The characteristics of the developed magnetic nanocomposites enable us to consider them as promising materials serving as a base for the development of targeted drug delivery systems.
About the authors
O. Yu. Golubeva
Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences
Author for correspondence.
Email: olga_isc@mail.ru
Russian Federation, St. Petersburg, 199034
E. Yu. Brazovskaya
Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences
Email: olga_isc@mail.ru
Russian Federation, St. Petersburg, 199034
Yu. A. Alikina
Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences; St. Petersburg State Institute of Technology (Technical University)
Email: olga_isc@mail.ru
Russian Federation, St. Petersburg, 199034; St. Petersburg, 190013
S. V. D’yachenko
St. Petersburg State Institute of Technology (Technical University)
Email: olga_isc@mail.ru
Russian Federation, St. Petersburg, 190013
A. I. Zhernovoi
St. Petersburg State Institute of Technology (Technical University)
Email: olga_isc@mail.ru
Russian Federation, St. Petersburg, 190013