Synthesis and Study of Nanocomposites Based on Beta Zeolite and Magnetite for Targeted Drug Delivery


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Abstract

Magnetic nanocomposites based on Beta zeolites and magnetite nanoparticles modified with polydiallyldimethylammonium chloride are synthesized under hydrothermal conditions. Particles of an average size of 100–200 nm characterized with magnetic moments and a high sorption capacity towards the model drug, thiamine hydrochloride (vitamin B1), are obtained. The characteristics of the developed magnetic nanocomposites enable us to consider them as promising materials serving as a base for the development of targeted drug delivery systems.

About the authors

O. Yu. Golubeva

Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences

Author for correspondence.
Email: olga_isc@mail.ru
Russian Federation, St. Petersburg, 199034

E. Yu. Brazovskaya

Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences

Email: olga_isc@mail.ru
Russian Federation, St. Petersburg, 199034

Yu. A. Alikina

Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences; St. Petersburg State Institute of Technology (Technical University)

Email: olga_isc@mail.ru
Russian Federation, St. Petersburg, 199034; St. Petersburg, 190013

S. V. D’yachenko

St. Petersburg State Institute of Technology (Technical University)

Email: olga_isc@mail.ru
Russian Federation, St. Petersburg, 190013

A. I. Zhernovoi

St. Petersburg State Institute of Technology (Technical University)

Email: olga_isc@mail.ru
Russian Federation, St. Petersburg, 190013

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