Synthesis of 1,2-Diazepines by the Bischler–Napieralski Reaction

详细

A new strategy has been proposed for the synthesis of 5H-[1]benzofuro[2,3-d][1,2]diazepines containing two aryl substituents in the diazepine fragment. The key stage of the synthesis is intramolecular cyclization of the corresponding hydrazides under the Bischler–Napieralski reaction conditions.