Synthesis of functional isoxazole and isothiazole derivatives from [(5-arylisoxazol-3-yl)methoxy]arylmethanols

E. A. Dikusar; S. K. Petkevich; A. V. Kletskov; E. A. Semenova; V. I. Potkin

doi:10.1134/S1070428016010127

Synthesis of functional isoxazole and isothiazole derivatives from [(5-arylisoxazol-3-yl)methoxy]arylmethanols

作者: Dikusar E.A.¹, Petkevich S.K.¹, Kletskov A.V.¹, Semenova E.A.¹, Potkin V.I.¹
隶属关系:
1. Institute of Physical Organic Chemistry
期: 卷 52, 编号 1 (2016)
页面: 61-68
栏目: Article
URL: https://journals.rcsi.science/1070-4280/article/view/213496
DOI: https://doi.org/10.1134/S1070428016010127
ID: 213496

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详细

A procedure has been developed for the synthesis of functional isoxazole and isothiazole derivatives by reduction of (5-aryl-1,2-oxazol-3-yl)methoxybenzaldehydes to (5-aryl-1,2-oxazol-3-yl)methoxyaryl-methanols and subsequent acylation of the latter with isoxazole- and isothiazolecarbonyl chlorides.