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Synthesis of functional isoxazole and isothiazole derivatives from [(5-arylisoxazol-3-yl)methoxy]arylmethanols


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Abstract

A procedure has been developed for the synthesis of functional isoxazole and isothiazole derivatives by reduction of (5-aryl-1,2-oxazol-3-yl)methoxybenzaldehydes to (5-aryl-1,2-oxazol-3-yl)methoxyaryl-methanols and subsequent acylation of the latter with isoxazole- and isothiazolecarbonyl chlorides.

About the authors

E. A. Dikusar

Institute of Physical Organic Chemistry

Author for correspondence.
Email: dikusar@ifoch.bas-net.by
Belarus, ul. Surganova 13, Minsk, 220072

S. K. Petkevich

Institute of Physical Organic Chemistry

Email: dikusar@ifoch.bas-net.by
Belarus, ul. Surganova 13, Minsk, 220072

A. V. Kletskov

Institute of Physical Organic Chemistry

Email: dikusar@ifoch.bas-net.by
Belarus, ul. Surganova 13, Minsk, 220072

E. A. Semenova

Institute of Physical Organic Chemistry

Email: dikusar@ifoch.bas-net.by
Belarus, ul. Surganova 13, Minsk, 220072

V. I. Potkin

Institute of Physical Organic Chemistry

Email: dikusar@ifoch.bas-net.by
Belarus, ul. Surganova 13, Minsk, 220072

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