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Synthesis of Symmetrical Bisisoquinolinediones


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Abstract

A method of synthesis of 1,1′-(alkanediyl)bis{3-cyano-4-[4,5,5-trimethyl-2-oxo-5H-furan-3-yl]-pyridin-2(1H)-ones} from the corresponding lactones is developed. The synthesized compounds undergo intramolecular cyclization to form symmetrical 7,7′-(alkanediyl)bis{5-amino-3,3-dimethylfuro[3,4-f]isoquinoline-1,6(3H,7H)-diones}.

About the authors

R. M. Hakobyan

Institute of Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry

Author for correspondence.
Email: robahakob@gmail.com
Armenia, pr. Azatutyan 26, Yerevan, 0014

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