Application of Suzuki-Miyaura Reaction in the Chemistry of Oxolan-2-ones


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Abstract

The reactions of 2-(2-chloroprop-2-en-1-yl)-5,5-dimethyloxolan-2-one with arylboronic acids in the presence of Pd(PPh3)4 and K2CO3 was used to synthesize novel oxolan-2-one derivatives—3-[(2-aryl)prop-2-en-1-yl]-5,5-dimethyloxolan-2-ones. The reaction conditions were optimized for the highest yields of the target products.

About the authors

T. V. Ghochikyan

Faculty of Chemistry

Email: msamvelyan@ysu.am
Armenia, ul. A. Manoogian 1, Yerevan, 0025

A. S. Vardanyan

Faculty of Chemistry; Institut für Chemie

Email: msamvelyan@ysu.am
Armenia, ul. A. Manoogian 1, Yerevan, 0025; Albert-Einstein-Straße 3a, Rostock, 18059

M. A. Samvelyan

Faculty of Chemistry

Author for correspondence.
Email: msamvelyan@ysu.am
Armenia, ul. A. Manoogian 1, Yerevan, 0025

A. S. Galstyan

Faculty of Chemistry

Email: msamvelyan@ysu.am
Armenia, ul. A. Manoogian 1, Yerevan, 0025

P. Langer

Institut für Chemie

Email: msamvelyan@ysu.am
Germany, Albert-Einstein-Straße 3a, Rostock, 18059

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