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Synthesis of New (2-Acetamido)phenylglyoxylamides Containing an Acetal Fragment


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Abstract

Mild opening of the five-membered ring in 1-acetylisatins by the action of an equimolar amount of 4,4-diethoxybutan-1-amine afforded 2-(2-acetamidophenyl)-N-(4,4-diethoxybutyl)-2-oxoacetamides in almost quantitative yield.

About the authors

A. V. Bogdanov

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Author for correspondence.
Email: abogdanov@inbox.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420029

A. S. Gazizov

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: abogdanov@inbox.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420029

A. V. Smolobochkin

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: abogdanov@inbox.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420029

V. F. Mironov

Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center

Email: abogdanov@inbox.ru
Russian Federation, ul. Arbuzova 8, Kazan, Tatarstan, 420029

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