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3-Polyfluoroalkyl-1,5-diphenylpyrazoles in Suzuki Cross-Coupling Reactions


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Abstract

Suzuki cross-coupling was used for modification of 3-polyfluoroalkyl-1-phenylpyrazoles at the position C4. The synthesized 4-bromo- and 4-phenyl derivatives showed antitubercular effect on pyrazinamide level.

About the authors

А. E. Ivanova

Postovskii Institute of Organic Synthesis, Ural Branch

Email: saloutin@ios.uran.ru
Russian Federation, ul. Akademicheskaya/S. Kovalevskoi 20/22, Yekaterinburg, 620990

Ya. V. Burgart

Postovskii Institute of Organic Synthesis, Ural Branch

Email: saloutin@ios.uran.ru
Russian Federation, ul. Akademicheskaya/S. Kovalevskoi 20/22, Yekaterinburg, 620990

V. I. Saloutin

Postovskii Institute of Organic Synthesis, Ural Branch

Author for correspondence.
Email: saloutin@ios.uran.ru
Russian Federation, ul. Akademicheskaya/S. Kovalevskoi 20/22, Yekaterinburg, 620990

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