Synthesis of Spiro[indole-3,2′-pyrroles] from Pyrrolopyrazinetriones and Aminocyclohexenones

Resumo

8-Benzoyl-2-phenyl-3,4-dihydropyrrolo[1,2-a]pyrazine-1,6,7(2H)-trione reacted with 3-(alkylamino)-5,5-dimethylcyclohex-2-en-1-ones to give 1-alkyl-1′-(2-anilinoethyl)-3′-benzoyl-4′-hydroxy-6,6-dimethyl-6,7-dihydrospiro[indole-3,2′-pyrrole]-2,4,5′(1H,1′H,5H)-triones.