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Synthesis of cyclohexyl isovalerate by carbonylation of isobutylene with carbon monoxide and cyclohexanol in the presence of Pd(PPh3)4‒PPh3‒TsOH and its antimicrobial activity


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Abstract

A procedure has been developed for the synthesis of cyclohexyl isovalerate by reaction of isobutylene with carbon monoxide and cyclohexanol in the presence of the three-component catalytic system Pd(PPh3)4‒PPh3‒TsOH. Cyclohexyl isovalerate showed a pronounced antibacterial activity.

About the authors

N. O. Appazov

Korkyt Ata Kyzylorda State University

Author for correspondence.
Email: nurasar.82@mail.ru
Kazakhstan, ul. Aiteke bi 29A, Kyzylorda, 120014

S. S. Seitzhanov

Korkyt Ata Kyzylorda State University

Email: nurasar.82@mail.ru
Kazakhstan, ul. Aiteke bi 29A, Kyzylorda, 120014

A. T. Zhunissov

Korkyt Ata Kyzylorda State University

Email: nurasar.82@mail.ru
Kazakhstan, ul. Aiteke bi 29A, Kyzylorda, 120014

R. A. Narmanova

Korkyt Ata Kyzylorda State University

Email: nurasar.82@mail.ru
Kazakhstan, ul. Aiteke bi 29A, Kyzylorda, 120014

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