Cascade cyclization of methyl 2-(azidomethyl)furan-3-carboxylates with 2-cyanoacetamides. Efficient synthesis of a new heterocyclic system, furo[3,2- e ][1,2,3]triazolo- [1,5- a ][1,3]diazepine

M. S. Yagodkina; G. G. Yakovenko; A. V. Bol’but; M. V. Vovk

doi:10.1134/S1070428017040261

Cascade cyclization of methyl 2-(azidomethyl)furan-3-carboxylates with 2-cyanoacetamides. Efficient synthesis of a new heterocyclic system, furo[3,2-e][1,2,3]triazolo- [1,5-a][1,3]diazepine

作者: Yagodkina M.S.¹, Yakovenko G.G.¹, Bol’but A.V.¹, Vovk M.V.¹
隶属关系:
1. Institute of Organic Chemistry
期: 卷 53, 编号 4 (2017)
页面: 634-636
栏目: Short Communications
URL: https://journals.rcsi.science/1070-4280/article/view/216150
DOI: https://doi.org/10.1134/S1070428017040261
ID: 216150

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Cascade cyclization of methyl 2-(azidomethyl)furan-3-carboxylate with 2-cyanoacetamides in the presence of 2 equiv of potassium tert-butoxide afforded a series of N-substituted 5-oxo-5,9-dihydro-4H-furo-[3,2-e][1,2,3]triazolo[1,5-a][1,3]diazepine-3-carboxamides.