Synthesis of new sulfonamide derivatives of thiazolo[3,2- a ]quinazolin-5-one

R. M. Shlenev; S. I. Filimonov; A. V. Tarasov; A. S. Danilova; P. A. Agat’ev

doi:10.1134/S1070428016010139

Synthesis of new sulfonamide derivatives of thiazolo[3,2-a]quinazolin-5-one

Authors: Shlenev R.M.¹, Filimonov S.I.¹, Tarasov A.V.¹, Danilova A.S.¹, Agat’ev P.A.¹
Affiliations:
1. Yaroslavl State Technical University
Issue: Vol 52, No 1 (2016)
Pages: 69-75
Section: Article
URL: https://journals.rcsi.science/1070-4280/article/view/213504
DOI: https://doi.org/10.1134/S1070428016010139
ID: 213504

Cite item

Full Text

Open Access
Restricted Access

Access granted
Restricted Access

Subscription Access

Abstract
About the authors
References
Supplementary files
Statistics

Abstract

A general procedure has been proposed for the synthesis of thiazolo[3,2-a]quinazolin-5-one derivatives containing a sulfonamide group on C⁷ via intramolecular nucleophilic substitution of halogen in 2-halo-5-sulfamoyl-N-(1,3-thiazol-2-yl)benzamides. The effects of the degree of activation of the initial compound and halogen nature on the yield of the target products have been analyzed.