Synthesis, Characterization, Molecular Docking, and Antimicrobial Activity of New Arylidene-Substituted Imidazoles
- 作者: Aparna Y.1, Sharada L.1, Subhashini N.1, Sreekanth S.1
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隶属关系:
- Department of Chemistry
- 期: 卷 89, 编号 6 (2019)
- 页面: 1202-1208
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222946
- DOI: https://doi.org/10.1134/S1070363219060161
- ID: 222946
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详细
The title compounds are synthesized by condensation of 2-[4-(arylidene)-5-oxo-4, 5-dihydrooxazol-2-yl]phenylacetate with aromatic amines in presence of the Vilsemeier Haack reagent. Structures of all compounds are elucidated from 1H and 13C NMR, IR, and mass spectra. The compounds are tested for their antibacterial activity. Molecular docking study is focused on the relative orientation and nature of bonding between imidazoles and bacterial protein.
作者简介
Y. Aparna
Department of Chemistry
Email: lnsharada@gmail.com
印度, Hyderabad, Telangana, 500007
L. Sharada
Department of Chemistry
编辑信件的主要联系方式.
Email: lnsharada@gmail.com
印度, Hyderabad, Telangana, 500007
N. Subhashini
Department of Chemistry
Email: lnsharada@gmail.com
印度, Hyderabad, Telangana, 500007
Sivan Sreekanth
Department of Chemistry
Email: lnsharada@gmail.com
印度, Hyderabad, Telangana, 500007