Synthesis of 4-hydroxy-5-methyl-2-[2-(4-oxo-4H-chromen-3-yl)ethenyl]-6H-1,3-oxazin-6-ones and their reaction with hydrazine
- 作者: Chernov N.1, Klyukin A.1, Ksenofontova G.1, Shchegolev A.1, Yakovlev I.1
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隶属关系:
- St. Petersburg State Chemical Pharmaceutical Academy
- 期: 卷 87, 编号 5 (2017)
- 页面: 952-956
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/219700
- DOI: https://doi.org/10.1134/S1070363217050103
- ID: 219700
如何引用文章
详细
4-Hydroxy-6H-1,3-oxazin-6-ones containing a 3-vinylchromone fragment in the 2-position were synthesized. The direction of their reactions with hydrazine hydrate was found to depend on the solvent nature. The reaction in protic solvents (methanol, acetic acid) resulted in recyclization of both oxazine ring to 1,2,4-triazole and pyranone ring to pyrazole. Aprotic acetonitrile favored attack of hydrazine exclusively on the oxazine ring, while the 3-vinylchromone fragment remained intact.
作者简介
N. Chernov
St. Petersburg State Chemical Pharmaceutical Academy
编辑信件的主要联系方式.
Email: nikita.chernov@pharminnotech.com
俄罗斯联邦, ul. Professora Popova 14A, St. Petersburg, 197376
A. Klyukin
St. Petersburg State Chemical Pharmaceutical Academy
Email: nikita.chernov@pharminnotech.com
俄罗斯联邦, ul. Professora Popova 14A, St. Petersburg, 197376
G. Ksenofontova
St. Petersburg State Chemical Pharmaceutical Academy
Email: nikita.chernov@pharminnotech.com
俄罗斯联邦, ul. Professora Popova 14A, St. Petersburg, 197376
A. Shchegolev
St. Petersburg State Chemical Pharmaceutical Academy
Email: nikita.chernov@pharminnotech.com
俄罗斯联邦, ul. Professora Popova 14A, St. Petersburg, 197376
I. Yakovlev
St. Petersburg State Chemical Pharmaceutical Academy
Email: nikita.chernov@pharminnotech.com
俄罗斯联邦, ul. Professora Popova 14A, St. Petersburg, 197376