Regioselectivity of the methanolysis of polychlorinated biphenyls
- 作者: Khaibulova T.1, Boyarskaya I.1, Polukeev V.2, Boyarskii V.1
-
隶属关系:
- St. Petersburg State University
- Institute of Experimental Medicine
- 期: 卷 86, 编号 10 (2016)
- 页面: 2318-2324
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/216338
- DOI: https://doi.org/10.1134/S1070363216100121
- ID: 216338
如何引用文章
详细
Regioselectivity of the methanolysis of lower polychlorinated biphenyls with sodium methoxide in a mixture of methanol and DMSO at 100–130°С was studied. It was found that 2,4,4'-tricholobiphenyl is much more reactive than 2,4-dichlorobiphenyl. This results in different mechanisms of substitution. 2,4-Dichlorobiphenyl reacts with sodium methoxide by the elimination–addition mechanism to form four monosubstitution products in comparable quantities. 2,4,4'-Trichlorobiphenyl reacts with the methodixe ion by the classical SNAr mechanism, with preferential substitution of the 2-chlorine atom.
作者简介
T. Khaibulova
St. Petersburg State University
Email: v.boiarskii@spbu.ru
俄罗斯联邦, Universitetskaya nab. 7–9, St. Petersburg, 199034
I. Boyarskaya
St. Petersburg State University
Email: v.boiarskii@spbu.ru
俄罗斯联邦, Universitetskaya nab. 7–9, St. Petersburg, 199034
V. Polukeev
Institute of Experimental Medicine
Email: v.boiarskii@spbu.ru
俄罗斯联邦, St. Petersburg
V. Boyarskii
St. Petersburg State University
编辑信件的主要联系方式.
Email: v.boiarskii@spbu.ru
俄罗斯联邦, Universitetskaya nab. 7–9, St. Petersburg, 199034