Synthesis, characterization, and antimicrobial activity of novel (E)-1-(aryl)-3-{3, 5-dimethoxy-4-[(1-(aryl)-1H-1,2,3-triazol-4-yl)methoxy]phenyl}prop-2-en-1-ones
- 作者: Subhashini N.1, Sravanthi C.1, Sravanthi K.1, Shivaraj 2
-
隶属关系:
- Department of Chemistry, University College of Technology
- Department of Chemistry, University College of Science
- 期: 卷 86, 编号 6 (2016)
- 页面: 1405-1411
- 栏目: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215406
- DOI: https://doi.org/10.1134/S107036321606027X
- ID: 215406
如何引用文章
详细
The new chalcone derivatives containing the 1,2,3-triazole ring system, namely, (E)-1-(aryl)-3-{3,5-dimethoxy-4-[(1-(aryl)-1H-1,2,3-triazol-4-yl)methoxy]phenyl}prop-2-en-1-ones, were synthesized in 65–88% yield by the “click chemistry” reactions of substituted acetophenones, 4-hydroxy-3,5-dimethoxy-benzaldehyde, and different substituted azides. The structure of the compounds was determined by the FT-IR, 1H NMR, 13C NMR, and mass spectroscopic analyses. Compounds 6a–6l were screened for in vitro antimicrobial activity by the agar disc diffusion method.
作者简介
N. Subhashini
Department of Chemistry, University College of Technology
编辑信件的主要联系方式.
Email: njsubhashini@yahoo.co.in
印度, Hyderabad, 500007
Ch. Sravanthi
Department of Chemistry, University College of Technology
Email: njsubhashini@yahoo.co.in
印度, Hyderabad, 500007
K. Sravanthi
Department of Chemistry, University College of Technology
Email: njsubhashini@yahoo.co.in
印度, Hyderabad, 500007
Shivaraj
Department of Chemistry, University College of Science
Email: njsubhashini@yahoo.co.in
印度, Hyderabad, 500007