Synthesis of N-Derivatives of Cytisine, Anabasine, and Salsoline Alkaloids with Pharmacophore 3-Aminopyridine-2(1H)-one and 5-Methyl-7-phenyloxazole[5,4-b]pyridine Cycles
- Autores: Palamarchuk I.1, Ogurtsova D.2, Seilkhanov T.3, Kulakov I.1
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Afiliações:
- Institute of Chemistry
- Omsk O.M. Dostoevskii State University
- Ualikhanov Kokshetau State University
- Edição: Volume 89, Nº 12 (2019)
- Páginas: 2487-2491
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/223222
- DOI: https://doi.org/10.1134/S1070363219120259
- ID: 223222
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Resumo
The reaction of nucleophilic substitution of 2-chloro-N-(6-methyl-2-oxo-4-phenyl-1,2-dihydropyridin-3-yl)acetamide and 2-(chloromethyl)-5-methyl-7-phenyloxazolo[5,4-b]pyridine with cytisine, anabasine, and salsoline alkaloids has afforded the corresponding derivatives. Structure of the obtained compounds has been confirmed by means of 1H and 13C NMR spectroscopy.
Sobre autores
I. Palamarchuk
Institute of Chemistry
Autor responsável pela correspondência
Email: i.v.palamarchuk@utmn.ru
Rússia, Tyumen, 625003
D. Ogurtsova
Omsk O.M. Dostoevskii State University
Email: i.v.palamarchuk@utmn.ru
Rússia, Omsk, 644077
T. Seilkhanov
Ualikhanov Kokshetau State University
Email: i.v.palamarchuk@utmn.ru
Cazaquistão, Kokshetau, 020000
I. Kulakov
Institute of Chemistry
Email: i.v.palamarchuk@utmn.ru
Rússia, Tyumen, 625003