Synthesis and Structure of Biologically Active 1,2-Bis(2-oxocycloalkyl)ethane-1,2-diones and 3,4-Dioxo-4-(2-oxocycloalkyl)butanoic Acid Esters
- Autores: Mukovoz P.1, Dankovtseva E.1, Mukovoz V.1, Abramova V.1, Korol’kova D.2, Sizentsov A.2, Danilova E.3
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Afiliações:
- All-Russian Research Institute of Phytopathology
- Orenburg State University
- Ivanovo State University of Chemistry and Technology
- Edição: Volume 89, Nº 1 (2019)
- Páginas: 8-13
- Seção: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222691
- DOI: https://doi.org/10.1134/S107036321901002X
- ID: 222691
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Resumo
A two-step procedure has been proposed for the synthesis of 1,2-bis(2-oxocycloalkyl)ethane-1,2-diones and 3,4-dioxo-4-(2-oxocycloalkyl)butanoic acid esters by condensation of cycloalkyl ketones with dimethyl oxalate or of alkyl acetates with dialkyl oxalates and cycloalkyl ketones, respectively. The structure of the synthesized compounds has been discussed on the basis of their IR, 1H NMR, and mass spectra, and their antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Salmonella typhimurium strains has been estimated.
Sobre autores
P. Mukovoz
All-Russian Research Institute of Phytopathology
Autor responsável pela correspondência
Email: mpp27@mail.ru
Rússia, ul. Institut 5, Bol’shie Vyazemy, Moscow oblast, 143050
E. Dankovtseva
All-Russian Research Institute of Phytopathology
Email: mpp27@mail.ru
Rússia, ul. Institut 5, Bol’shie Vyazemy, Moscow oblast, 143050
V. Mukovoz
All-Russian Research Institute of Phytopathology
Email: mpp27@mail.ru
Rússia, ul. Institut 5, Bol’shie Vyazemy, Moscow oblast, 143050
V. Abramova
All-Russian Research Institute of Phytopathology
Email: mpp27@mail.ru
Rússia, ul. Institut 5, Bol’shie Vyazemy, Moscow oblast, 143050
D. Korol’kova
Orenburg State University
Email: mpp27@mail.ru
Rússia, pr. Pobedy 13, Orenburg, 460018
A. Sizentsov
Orenburg State University
Email: mpp27@mail.ru
Rússia, pr. Pobedy 13, Orenburg, 460018
E. Danilova
Ivanovo State University of Chemistry and Technology
Email: mpp27@mail.ru
Rússia, Sheremetevskii pr. 7, Ivanovo, 153000
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