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Synthesis, structure, and antimicrobial activity of N,6-diaryl-4-methyl-2-oxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides


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Resumo

Reactions of acetoacetic acid N-arylamides with aromatic aldehydes and urea led to the formation of N,6-diaryl-4-methyl-2-oxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides. Structure and antimicrobial activity of the compounds obtained were examined.

Sobre autores

V. Gein

Perm State Pharmaceutical Academy

Autor responsável pela correspondência
Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614990

T. Zamaraeva

Perm State Pharmaceutical Academy

Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614990

A. Fedotov

Perm State Pharmaceutical Academy

Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614990

A. Balandina

Perm State Pharmaceutical Academy

Email: geinvl48@mail.ru
Rússia, ul. Polevaya 2, Perm, 614990

M. Dmitriev

Perm State National Research University

Email: geinvl48@mail.ru
Rússia, Perm

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Declaração de direitos autorais © Pleiades Publishing, Ltd., 2016