Synthesis, Structure, and Biological Activity of Magnesium(II), Zinc(II), Cobalt(II), and Copper(II) Bis(4-aryl-1-ethoxy-1-oxobutane-2,4-dionates)

E. A. Kunavina; V. O. Koz’minykh; A. N. Sizentsov; E. V. Salikova; M. L. Rusyaeva; D. S. Korol’kova

doi:10.1134/S1070363219010122

Synthesis, Structure, and Biological Activity of Magnesium(II), Zinc(II), Cobalt(II), and Copper(II) Bis(4-aryl-1-ethoxy-1-oxobutane-2,4-dionates)

Авторлар: Kunavina E.¹, Koz’minykh V.², Sizentsov A.¹, Salikova E.¹, Rusyaeva M.¹, Korol’kova D.¹
Мекемелер:
1. Orenburg State University
2. Perm State Humanitarian Pedagogical University
Шығарылым: Том 89, № 1 (2019)
Беттер: 67-70
Бөлім: Article
URL: https://journals.rcsi.science/1070-3632/article/view/222703
DOI: https://doi.org/10.1134/S1070363219010122
ID: 222703

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Аннотация

The condensation of aryl methyl ketones with diethyl oxalate in the presence of metallic sodium or sodium hydride gave sodium 4-aryl-1-ethoxy-1,4-dioxobut-2-en-2-olates, and metal exchange of the latter with magnesium(II), zinc(II), cobalt(II), and copper(II) salts afforded the corresponding metal bis(4-aryl-1-ethoxy-1-oxobutane-2,4-dionates). The obtained complexes were tested for antibacterial activity against gram-positive and gram-negative bacteria by the agar diffusion method.