Spatial Structure of Tetrasubstituted Thiacalix[4]arenes Containing L-Tryptophan Fragments in Solution
- Авторлар: Padnya P.1, Potrekeeva O.1, Bayarashov E.1, Stoikov I.1
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Мекемелер:
- Butlerov Chemical Institute
- Шығарылым: Том 88, № 11 (2018)
- Беттер: 2328-2334
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222534
- DOI: https://doi.org/10.1134/S1070363218110130
- ID: 222534
Дәйексөз келтіру
Аннотация
The steric structure of the cone and 1,3-alternate stereoisomers of p-tert-butylthiacalix[4]arenes bearing in the lower rim four substituents containing amide and ammonium groups as well as L-tryptophan residues was studied by 1Н, 13С, 1Н–1Н NOESY, and 1Н–13С HSQC NMR spectroscopy. The mutual repulsion of the charged ammonium groups and the presence of intramolecular hydrogen bonds in the synthesized compounds can make the peptide bond with the tryptophan residue sterically accessible for enzymes.
Негізгі сөздер
Авторлар туралы
P. Padnya
Butlerov Chemical Institute
Email: ivan.stoikov@mail.ru
Ресей, ul. Kremlevskaya 18, Kazan, Tatarstan, 420008
O. Potrekeeva
Butlerov Chemical Institute
Email: ivan.stoikov@mail.ru
Ресей, ul. Kremlevskaya 18, Kazan, Tatarstan, 420008
E. Bayarashov
Butlerov Chemical Institute
Email: ivan.stoikov@mail.ru
Ресей, ul. Kremlevskaya 18, Kazan, Tatarstan, 420008
I. Stoikov
Butlerov Chemical Institute
Хат алмасуға жауапты Автор.
Email: ivan.stoikov@mail.ru
Ресей, ul. Kremlevskaya 18, Kazan, Tatarstan, 420008