Synthesis of pyrinidine-2,4(1H,3H)-dione derivatives containing N-alkyl substituents
- Авторлар: Valiev V.1, Ozden I.1, Meshcheryakova S.2, Spirikhin L.3, Zlotskii S.1, Raskildina G.1
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Мекемелер:
- Ufa State Petroleum Technological University
- Bashkir State Medical University
- Ufa Institute of Chemistry
- Шығарылым: Том 87, № 8 (2017)
- Беттер: 1872-1875
- Бөлім: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/221173
- DOI: https://doi.org/10.1134/S1070363217080369
- ID: 221173
Дәйексөз келтіру
Аннотация
6-Methyluracil derivatives containing a gem-dichlorocyclopropane and a 1,3-dioxolane fragments were synthesized for the first time. The condensation of 6-methyluracil with chloromethyl derivatives gives a mixture of N1- and N3-monosubstituted products, and the profound N-alkylation of this compound provides disubstituted uracils. The structure of the synthesized compounds was studied by H1 and 13С NMR spectroscopy and their relative antioxidant activity was evaluated by luminol-dependent chemiluminescence measurements.
Авторлар туралы
V. Valiev
Ufa State Petroleum Technological University
Email: graskildina444@mail.ru
Ресей, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062
I. Ozden
Ufa State Petroleum Technological University
Email: graskildina444@mail.ru
Ресей, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062
S. Meshcheryakova
Bashkir State Medical University
Email: graskildina444@mail.ru
Ресей, Ufa, Bashkortostan
L. Spirikhin
Ufa Institute of Chemistry
Email: graskildina444@mail.ru
Ресей, Ufa, Bashkortostan
S. Zlotskii
Ufa State Petroleum Technological University
Email: graskildina444@mail.ru
Ресей, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062
G. Raskildina
Ufa State Petroleum Technological University
Хат алмасуға жауапты Автор.
Email: graskildina444@mail.ru
Ресей, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062