Email this article Stereoselective Bioreduction of Hexan-2-one into (2S)-(+)-Hexan-2-ol
- Authors: Chanysheva A.R.1, Sheiko E.A.1, Zorin V.V.1
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Affiliations:
- Ufa State Petroleum Technological University
- Issue: Vol 88, No 13 (2018)
- Pages: 2934-2936
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/222674
- DOI: https://doi.org/10.1134/S1070363218130170
- ID: 222674
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Abstract
A method for the synthesis of (2S)-(+)-hexan-2-ol, the precursor of a series of drugs, by the enantioselective bioreduction of the prochiral hexan-2-one is proposed. The use of various exogenous reducing agents (isopropanol, ethanol, and glucose) for increasing the yield of the target (2S)-(+)-hexan-2-ol and the enantioselectivity of the bioreduction of hexane-2-one are investigated.
About the authors
A. R. Chanysheva
Ufa State Petroleum Technological University
Author for correspondence.
Email: aliyach@mail.ru
Russian Federation, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062
E. A. Sheiko
Ufa State Petroleum Technological University
Email: aliyach@mail.ru
Russian Federation, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062
V. V. Zorin
Ufa State Petroleum Technological University
Email: aliyach@mail.ru
Russian Federation, ul. Kosmonavtov 1, Ufa, Bashkortostan, 450062
