Synthesis and reactions of some novel 1-(2,7-dimethyl-1,8-naphthyridin-4-yl)hydrazine candidates
- Authors: Khalifa N.M.1,2, Al-Omar M.A.1, Ahmed N.S.2,3
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Affiliations:
- Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy
- Therapeutically Chemistry Department, Pharmaceutical and Drug Industries Division
- Chemistry Department, Faculty of Science
- Issue: Vol 87, No 10 (2017)
- Pages: 2462-2466
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/221501
- DOI: https://doi.org/10.1134/S1070363217100292
- ID: 221501
Cite item
Abstract
A series of novel 1,8-naphthyridine derivatives containing Schiff bases and amino substituents were synthesized starting from the reaction of 4-hydrazinyl-2,7-dimethyl-1,8-naphthyridine with different active carbonyl groups, acid monoanhydrides and tetracarboxylic acid anhydrides. Structures of new compounds were elucidated by means of physical and spectroscopic analyses.
Keywords
About the authors
N. M. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy; Therapeutically Chemistry Department, Pharmaceutical and Drug Industries Division
Author for correspondence.
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Dokki, Cairo, 12622
M. A. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration and Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451
N. S. Ahmed
Therapeutically Chemistry Department, Pharmaceutical and Drug Industries Division; Chemistry Department, Faculty of Science
Email: nagykhalifa@hotmail.com
Egypt, Dokki, Cairo, 12622; Jeddah, 21589