One-pot multicomponent synthesis of 4-(7-cyclohepta-1,3,5-trienyl)aniline derivatives
- Authors: Akent’eva T.A.1, Makhmudov R.R.2
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Affiliations:
- Pryanishnikov Perm State Agricultural Academy
- Perm State National Research University
- Issue: Vol 87, No 7 (2017)
- Pages: 1631-1633
- Section: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/220903
- DOI: https://doi.org/10.1134/S1070363217070301
- ID: 220903
Cite item
Abstract
Reaction of aromatic aldehydes with aniline and tropylium tetrafluoroborate yielded N-arylmethylene-4-(7-cyclohepta-1,3,5-trienyl)anilines, while reaction of aromatic aldehydes with aniline, tropylium tetrafluoroborate, and sodium tetrahydroborate afforded N-arylmethyl-4-(7-cyclohepta-1,3,5-trienyl)anilines. Two most promising compounds, N-2-hydroxyphenylmethylene-4′-(7-cyclohepta-1,3,5-trienyl)aniline and N-2-hydroxyphenylmethyl-4′-(7-cyclohepta-1,3,5-trienyl)aniline, were tested for acute toxicity (LD50) and their low toxicity was revealed.
About the authors
T. A. Akent’eva
Pryanishnikov Perm State Agricultural Academy
Author for correspondence.
Email: akentjeva-perm@rambler.ru
Russian Federation, ul. Petropavlovskaya 23, Perm, 614000
R. R. Makhmudov
Perm State National Research University
Email: akentjeva-perm@rambler.ru
Russian Federation, Perm