电邮这篇文章 Pentapeptide analogs of somatostatin containing a thiazolidine fragment: synthesis and cytotoxic activity
- 作者: Balaev A.1, Osipov V.1,2, Okhmanovich K.1, Ruchko E.1, Baryshnikova M.3, Khachatryan D.2
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隶属关系:
- Pharm-Sintez
- State Scientific-Research Institute of Chemical Reagents and High Purity Substances (IREA)
- N. N. Blokhin Russian Cancer Scientific Center, Ministry of Healthcare of Russian Federation
- 期: 卷 65, 编号 12 (2016)
- 页面: 2948-2951
- 栏目: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/239692
- DOI: https://doi.org/10.1007/s11172-016-1683-6
- ID: 239692
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详细
Pentapeptide analogs of somatostatin containing an (R)-1,3-thiazolidine fragment (Thz) of the general formula X—Thz—Phe—D-Trp—Lys(Y)—Thr—Z were synthesized for the first time. The synthesized compounds were tested for cytotoxic activity against three cancer cell lines (MCF-7, PC3, and HCT-116) and against human embryo fibroblasts.
作者简介
A. Balaev
Pharm-Sintez
Email: derenik-s@yandex.ru
俄罗斯联邦, 29, Build. 134, ul. Vereiskaya, Moscow, 121357
V. Osipov
Pharm-Sintez; State Scientific-Research Institute of Chemical Reagents and High Purity Substances (IREA)
Email: derenik-s@yandex.ru
俄罗斯联邦, 29, Build. 134, ul. Vereiskaya, Moscow, 121357; 3 ul. Bogorodsky val, Moscow, 107076
K. Okhmanovich
Pharm-Sintez
Email: derenik-s@yandex.ru
俄罗斯联邦, 29, Build. 134, ul. Vereiskaya, Moscow, 121357
E. Ruchko
Pharm-Sintez
Email: derenik-s@yandex.ru
俄罗斯联邦, 29, Build. 134, ul. Vereiskaya, Moscow, 121357
M. Baryshnikova
N. N. Blokhin Russian Cancer Scientific Center, Ministry of Healthcare of Russian Federation
Email: derenik-s@yandex.ru
俄罗斯联邦, 23 Kashirskoe shosse, Moscow, 115478
D. Khachatryan
State Scientific-Research Institute of Chemical Reagents and High Purity Substances (IREA)
编辑信件的主要联系方式.
Email: derenik-s@yandex.ru
俄罗斯联邦, 3 ul. Bogorodsky val, Moscow, 107076
