Synthesis of ethynyl-3-hydroxyquinoline-4-carboxylic acids


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3-Hydroxyquinoline-4-carboxylic acids containing ethynyl moiety in the 6th and 8th positions were obtained for the fi rst time. A synthetic approach to aforementioned compounds based on the Sonogashira cross-coupling and the Pfi tzinger reaction was developed. Physicochemical properties of the newly synthesized structures were investigated.

Sobre autores

S. Maklakova

Department of Chemistry, M. V. Lomonosov Moscow State University; Laboratory of biomedical nanomaterials, National University of Science and Technology MISiS

Autor responsável pela correspondência
Email: MaklakovaSU@yandex.ru
Rússia, Build. 3, 1 Leninskie Gory, Moscow, 119991; 4 Leninskiy prosp., Moscow, 119049

A. Chuprov

Department of Chemistry, M. V. Lomonosov Moscow State University

Email: MaklakovaSU@yandex.ru
Rússia, Build. 3, 1 Leninskie Gory, Moscow, 119991

M. Mazhuga

Department of Chemistry, M. V. Lomonosov Moscow State University

Email: MaklakovaSU@yandex.ru
Rússia, Build. 3, 1 Leninskie Gory, Moscow, 119991

E. Beloglazkina

Department of Chemistry, M. V. Lomonosov Moscow State University

Email: MaklakovaSU@yandex.ru
Rússia, Build. 3, 1 Leninskie Gory, Moscow, 119991

N. Zyk

Department of Chemistry, M. V. Lomonosov Moscow State University

Email: MaklakovaSU@yandex.ru
Rússia, Build. 3, 1 Leninskie Gory, Moscow, 119991

A. Majouga

Department of Chemistry, M. V. Lomonosov Moscow State University; D. I. Mendeleev University of Chemical Technology of Russia; Laboratory of biomedical nanomaterials, National University of Science and Technology MISiS

Email: MaklakovaSU@yandex.ru
Rússia, Build. 3, 1 Leninskie Gory, Moscow, 119991; 9 Miusskaya pl., Moscow, 125047; 4 Leninskiy prosp., Moscow, 119049

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