Folic acid and its derivatives for targeted photodynamic therapy of cancer
- Авторы: Suvorov N.V.1, Mironov A.F.1, Grin M.A.1
- 
							Учреждения: 
							- Moscow Technological University, Institute of Fine Chemical Technologies
 
- Выпуск: Том 66, № 11 (2017)
- Страницы: 1982-2008
- Раздел: Review
- URL: https://journals.rcsi.science/1066-5285/article/view/241498
- DOI: https://doi.org/10.1007/s11172-017-1973-7
- ID: 241498
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Аннотация
The fundamentals of folic acid and folate receptors functioning in the body, changes in the expression level of folate receptors in carcinogenesis, as well as use of folic acid and its derivatives for targeted delivery of photosensitizers to tumors have been reviewed. The ways of increasing the efficacy of photodynamic therapy by creating multifunctional nanoplatforms that ensure both passive targeting and receptor-mediated internalization of photosensitizers in tumor cells have been discussed.
Об авторах
N. Suvorov
Moscow Technological University, Institute of Fine Chemical Technologies
														Email: michael_grin@mail.ru
				                					                																			                												                	Россия, 							86 prosp. Vernadskogo, Moscow, 119571						
A. Mironov
Moscow Technological University, Institute of Fine Chemical Technologies
														Email: michael_grin@mail.ru
				                					                																			                												                	Россия, 							86 prosp. Vernadskogo, Moscow, 119571						
M. Grin
Moscow Technological University, Institute of Fine Chemical Technologies
							Автор, ответственный за переписку.
							Email: michael_grin@mail.ru
				                					                																			                												                	Россия, 							86 prosp. Vernadskogo, Moscow, 119571						
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