Hydroxyketones in the thiadiazine cycle formation


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Cyclocondensation of 1-hydroxyketones with thiosemicarbazide resulted in thiadiazines. Nitrate ester of 1-hydroxyketone reacted under similar conditions to give the corresponding thiosemicarbazone. In the case of bromoacetyl-substituted nitrate ester of 1-hydroxyketone, condensation proceeded via intramolecular reaction between the thiol and bromomethyl groups.

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E. Pulatov

V. I. Nikitin Institute of Chemistry, Academy of Sciences of the Republic of Tajikistan

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Email: coordin@yandex.ru
塔吉克斯坦, 299/2 ul. Aini, Dushanbe, 734063

M. Isobaev

V. I. Nikitin Institute of Chemistry, Academy of Sciences of the Republic of Tajikistan

Email: coordin@yandex.ru
塔吉克斯坦, 299/2 ul. Aini, Dushanbe, 734063

B. Mavlonov

V. I. Nikitin Institute of Chemistry, Academy of Sciences of the Republic of Tajikistan

Email: coordin@yandex.ru
塔吉克斯坦, 299/2 ul. Aini, Dushanbe, 734063

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