Synthesis and membrane-protective activity of 4-aminomethyl derivatives of 2,6-diisobornylphenol

Resumo

A series of 4-aminomethyl derivatives of 2,6-diisobornylphenol containing tertiary and secondary amino groups were synthesized. Their toxicity and the membrane-protective and antioxidant activity were assessed using red blood cells of laboratory mice as the test object. These compounds were shown to exhibit high membrane-protective and antioxidant activity, which substantially depends on the structure of the substituent and the concentration of the substance.