Enviar artigo por via de e-mail Hydroxamic acids: synthesis and adjuvant activity in combinatorial anticancer therapy
- Autores: Fedorov B.S.1, Fadeev M.A.1, Eremeev A.B.1, Konovalova N.P.1, Bogdanov G.N.1, Tatyanenko L.V.1, Sashenkova T.E.1, Mishchenko D.V.1
-
Afiliações:
- Institute of Problems of Chemical Physics, Russian Academy of Sciences
- Edição: Volume 65, Nº 3 (2016)
- Páginas: 801-805
- Seção: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/237682
- DOI: https://doi.org/10.1007/s11172-016-1377-0
- ID: 237682
Citar
Acesso aberto
Acesso está concedido
Somente assinantes
Resumo
Monoand disubstituted N-hydroxyamides of dicarboxylic acids were prepared by reaction of dicarboxylic acids or acid anhydrides with hydroxylamine. The use of these compounds in combinatorial cytostatic therapy of implanted tumors with cisplatin or cyclophosphamide totally inhibits metastasis formation in B16 melanoma and Lewis lung carcinoma, and resulted in 100% survival of leukemic animals.
Sobre autores
B. Fedorov
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Autor responsável pela correspondência
Email: boris-45@inbox.ru
Rússia, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
M. Fadeev
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Rússia, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
A. Eremeev
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Rússia, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
N. Konovalova
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Rússia, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
G. Bogdanov
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Rússia, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
L. Tatyanenko
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Rússia, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
T. Sashenkova
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Rússia, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
D. Mishchenko
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: boris-45@inbox.ru
Rússia, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432
Arquivos suplementares
