Synthesis and evaluation of the influence of 5-sulfanyl-1,2,3-triazol-1-ylaminocarboxylic acid derivatives on kinetics of ascorbic acid oxidation

V. V. Emelianov; A. V. Musalnikova; E. A. Savateeva; Yu. S. Shakhmina; T. A. Kalinina; T. V. Glukhareva; Yu. Yu. Morzherin

doi:10.1007/s11172-016-1285-3

Synthesis and evaluation of the influence of 5-sulfanyl-1,2,3-triazol-1-ylaminocarboxylic acid derivatives on kinetics of ascorbic acid oxidation

Autores: Emelianov V.V.¹, Musalnikova A.V.¹, Savateeva E.A.¹, Shakhmina Y.S.¹, Kalinina T.A.¹, Glukhareva T.V.¹, Morzherin Y.Y.¹
Afiliações:
1. Ural Federal University
Edição: Volume 65, Nº 1 (2016)
Páginas: 203-208
Seção: Full Articles
URL: https://journals.rcsi.science/1066-5285/article/view/236903
DOI: https://doi.org/10.1007/s11172-016-1285-3
ID: 236903

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1,2,3-Thiadiazolylureas containing amino acid residues were synthesized. These compounds were converted to 5-sulfanyl-1,2,3-triazol-1-ylaminocarboxylic acid sodium salts under alkaline conditions. These salts were found to inhibit the oxidation of ascorbic acid with air oxygen. In the presence of the equimolar amount of 5-sulfanyl-1,2,3-triazoles, the rate of diminution of ascorbic acid decreased by 1.5—3 times, whereas in the case of their two-fold excess by a factor of 5.