Email this article Synthesis of 5,4″-di-O-succinoylavermectin B1
- Authors: Chernoburova E.I.1, Danchenko K.V.1, Shchetinina M.A.1, Zharov A.A.1, Kolobov A.V.2, Dzhafarov M.K.3, Vasilevich F.I.3, Zavarzin I.V.1
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Affiliations:
- N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
- Yaroslavl State Technical University
- K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology
- Issue: Vol 65, No 12 (2016)
- Pages: 2952-2955
- Section: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/239706
- DOI: https://doi.org/10.1007/s11172-016-1684-5
- ID: 239706
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Abstract
A reaction of avermectin B1 with succinic anhydride at ultrahigh pressure (10 kbar) gave previously unavailable 5,4″-di-O-succinoylavermectin B1, which is of interest as potential antiparasitic agent.
About the authors
E. I. Chernoburova
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Russian Federation, 47 Leninsky prosp., Moscow, 119991
K. V. Danchenko
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Russian Federation, 47 Leninsky prosp., Moscow, 119991
M. A. Shchetinina
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Russian Federation, 47 Leninsky prosp., Moscow, 119991
A. A. Zharov
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Russian Federation, 47 Leninsky prosp., Moscow, 119991
A. V. Kolobov
Yaroslavl State Technical University
Email: zavi@ioc.ac.ru
Russian Federation, 88 Moskovskii prosp., Yaroslavl, 150023
M. Kh. Dzhafarov
K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology
Email: zavi@ioc.ac.ru
Russian Federation, 23 ul. Akad. Skryabina, Moscow, 119991
F. I. Vasilevich
K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology
Email: zavi@ioc.ac.ru
Russian Federation, 23 ul. Akad. Skryabina, Moscow, 119991
I. V. Zavarzin
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Author for correspondence.
Email: zavi@ioc.ac.ru
Russian Federation, 47 Leninsky prosp., Moscow, 119991
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