Synthesis of 5,4″-di-O-succinoylavermectin B1


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A reaction of avermectin B1 with succinic anhydride at ultrahigh pressure (10 kbar) gave previously unavailable 5,4″-di-O-succinoylavermectin B1, which is of interest as potential antiparasitic agent.

作者简介

E. Chernoburova

N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Email: zavi@ioc.ac.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991

K. Danchenko

N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Email: zavi@ioc.ac.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991

M. Shchetinina

N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Email: zavi@ioc.ac.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991

A. Zharov

N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Email: zavi@ioc.ac.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991

A. Kolobov

Yaroslavl State Technical University

Email: zavi@ioc.ac.ru
俄罗斯联邦, 88 Moskovskii prosp., Yaroslavl, 150023

M. Dzhafarov

K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology

Email: zavi@ioc.ac.ru
俄罗斯联邦, 23 ul. Akad. Skryabina, Moscow, 119991

F. Vasilevich

K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology

Email: zavi@ioc.ac.ru
俄罗斯联邦, 23 ul. Akad. Skryabina, Moscow, 119991

I. Zavarzin

N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

编辑信件的主要联系方式.
Email: zavi@ioc.ac.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991

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