Chemical transformations of bacteriochlorophyll a and its medical applications


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Abstract

The review is devoted to methods of targeted chemical modifications of bacteriochlorophyll a. These methods provide an approach to the synthesis of derivatives with improved photophysical properties and increased hydrophilicity and are suited to the design of conjugates with other biologically active molecules utilized for fluorescence diagnosis and binary cancer therapy.

About the authors

M. A. Grin

Institute of Fine Chemical Technologies, Moscow Technological University

Author for correspondence.
Email: michael_grin@mail.ru
Russian Federation, 86 prosp. Vernadskogo, Moscow, 119571

A. F. Mironov

Institute of Fine Chemical Technologies, Moscow Technological University

Email: michael_grin@mail.ru
Russian Federation, 86 prosp. Vernadskogo, Moscow, 119571


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