Enviar artigo por via de e-mail Synthesis of glutaryl-containing derivatives of GRGD and KRGD peptides
- Autores: Demin A.M.1, Vakhrushev A.V.1, Tumashov A.A.1,2, Krasnov V.P.1
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Afiliações:
- I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Institute of Natural Sciences and Mathematics, Ural Federal University
- Edição: Volume 68, Nº 12 (2019)
- Páginas: 2316-2324
- Seção: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/243565
- DOI: https://doi.org/10.1007/s11172-019-2705-y
- ID: 243565
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Resumo
New derivatives of tetrapeptides GRGD (Gly-Arg(Pbf)-Gly-Asp(OMe)-OMe) and KRGD (Boc-Lys-Arg(Pbf)-Gly-Asp(OMe)-OMe) containing a glutaric acid fragment as a linker were synthesized. The linker provides the possibility for binding these derivatives to other biologically active molecules or nanoparticles.
Sobre autores
A. Demin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Autor responsável pela correspondência
Email: demin@ios.uran.ru
Rússia, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990
A. Vakhrushev
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: demin@ios.uran.ru
Rússia, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990
A. Tumashov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Institute of Natural Sciences and Mathematics, Ural Federal University
Email: demin@ios.uran.ru
Rússia, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990; 19 ul. Mira, Ekaterinburg, 620002
V. Krasnov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: demin@ios.uran.ru
Rússia, 22 ul. S. Kovalevskoi, Ekaterinburg, 620990
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