Email this article Novel derivatives of 3,5-di-tert-butylpyrocatechol with pharmacophore substituents
- Authors: Ukhin L.Y.1, Kuz´mina L.G.2, Alexeenko D.V.1, Belousova L.V.1, Morkovnik A.S.1, Shepelenko E.N.3, Podshibyakin V.A.1, Borodkin G.S.1, Dmitrieva O.I.1
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Affiliations:
- Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University
- N. S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences
- Federal Research Center Southern Scientific Center of the Russian Academy of Sciences
- Issue: Vol 68, No 12 (2019)
- Pages: 2290-2297
- Section: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/243562
- DOI: https://doi.org/10.1007/s11172-019-2702-1
- ID: 243562
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Abstract
New potentially bioactive derivatives comprising spatially hindered pyrocatechol linked to hydrazine, acid hydrazides (including isoniazid), and acetylcysteine by a covalent bridge, have been obtained. The structure of the obtained compounds was studied by X-ray diffraction analysis.
About the authors
L. Yu. Ukhin
Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University
Author for correspondence.
Email: lyukhin@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov-on-Don, 344090
L. G. Kuz´mina
N. S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences
Email: lyukhin@ipoc.sfedu.ru
Russian Federation, 31 Leninsky prosp., Moscow, 119991
D. V. Alexeenko
Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University
Email: lyukhin@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov-on-Don, 344090
L. V. Belousova
Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University
Email: lyukhin@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov-on-Don, 344090
A. S. Morkovnik
Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University
Email: lyukhin@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov-on-Don, 344090
E. N. Shepelenko
Federal Research Center Southern Scientific Center of the Russian Academy of Sciences
Email: lyukhin@ipoc.sfedu.ru
Russian Federation, 41 ul. Chekhova, Rostov-on-Don, 344006
V. A. Podshibyakin
Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University
Email: lyukhin@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov-on-Don, 344090
G. S. Borodkin
Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University
Email: lyukhin@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov-on-Don, 344090
O. I. Dmitrieva
Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University
Email: lyukhin@ipoc.sfedu.ru
Russian Federation, 194/2 prosp. Stachki, Rostov-on-Don, 344090
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