Novel derivatives of 3,5-di-tert-butylpyrocatechol with pharmacophore substituents


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New potentially bioactive derivatives comprising spatially hindered pyrocatechol linked to hydrazine, acid hydrazides (including isoniazid), and acetylcysteine by a covalent bridge, have been obtained. The structure of the obtained compounds was studied by X-ray diffraction analysis.

Sobre autores

L. Ukhin

Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University

Autor responsável pela correspondência
Email: lyukhin@ipoc.sfedu.ru
Rússia, 194/2 prosp. Stachki, Rostov-on-Don, 344090

L. Kuz´mina

N. S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences

Email: lyukhin@ipoc.sfedu.ru
Rússia, 31 Leninsky prosp., Moscow, 119991

D. Alexeenko

Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University

Email: lyukhin@ipoc.sfedu.ru
Rússia, 194/2 prosp. Stachki, Rostov-on-Don, 344090

L. Belousova

Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University

Email: lyukhin@ipoc.sfedu.ru
Rússia, 194/2 prosp. Stachki, Rostov-on-Don, 344090

A. Morkovnik

Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University

Email: lyukhin@ipoc.sfedu.ru
Rússia, 194/2 prosp. Stachki, Rostov-on-Don, 344090

E. Shepelenko

Federal Research Center Southern Scientific Center of the Russian Academy of Sciences

Email: lyukhin@ipoc.sfedu.ru
Rússia, 41 ul. Chekhova, Rostov-on-Don, 344006

V. Podshibyakin

Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University

Email: lyukhin@ipoc.sfedu.ru
Rússia, 194/2 prosp. Stachki, Rostov-on-Don, 344090

G. Borodkin

Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University

Email: lyukhin@ipoc.sfedu.ru
Rússia, 194/2 prosp. Stachki, Rostov-on-Don, 344090

O. Dmitrieva

Scientific Research Institute of Physical and Organic Chemistry, Southern Federal University

Email: lyukhin@ipoc.sfedu.ru
Rússia, 194/2 prosp. Stachki, Rostov-on-Don, 344090

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