Development of new antituberculosis drugs among of 1,3- and 1,4-diazines. Highlights and perspectives


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Abstract

The properties of pyrimidine and pyrazine derivatives responsible for the existence of antituberculosis activity are considered. Examples of synthesis and biological activity of the most promising compounds containing the pyrimidine or pyrazine rings in the molecular structure are presented.

About the authors

E. V. Verbitskiy

I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin

Author for correspondence.
Email: Verbitsky@ios.uran.ru
Russian Federation, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620137; 9 ul. Mira, Ekaterinburg, 620002

G. L. Rusinov

I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin

Email: Verbitsky@ios.uran.ru
Russian Federation, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620137; 9 ul. Mira, Ekaterinburg, 620002

V. N. Charushin

I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin

Email: Verbitsky@ios.uran.ru
Russian Federation, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620137; 9 ul. Mira, Ekaterinburg, 620002

O. N. Chupakhin

I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin

Email: Verbitsky@ios.uran.ru
Russian Federation, 22/20 ul. S. Kovalevskoi, Ekaterinburg, 620137; 9 ul. Mira, Ekaterinburg, 620002

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