Macrocycle-based oligo- and polylactides: synthesis and prospects of application

I. I. Stoikov; P. L. Padnya; O. A. Mostovaya; A. A. Vavilova; V. V. Gorbachuk; D. N. Shurpik; G. A. Evtugin

doi:10.1007/s11172-019-2655-4

Macrocycle-based oligo- and polylactides: synthesis and prospects of application

Authors: Stoikov I.I.¹, Padnya P.L.¹, Mostovaya O.A.¹, Vavilova A.A.¹, Gorbachuk V.V.¹, Shurpik D.N.¹, Evtugin G.A.¹
Affiliations:
1. A. M. Butlerov Chemical Institute, Kazan Federal University
Issue: Vol 68, No 11 (2019)
Pages: 1962-1982
Section: Reviews
URL: https://journals.rcsi.science/1066-5285/article/view/243516
DOI: https://doi.org/10.1007/s11172-019-2655-4
ID: 243516

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Abstract

The review considers methods for modifying oligo- and polymers of lactic acid by macrocyclic moieties (cyclodextrin, tetrapyrrole, and calixarene) and the effect of modifiers on the complexing, thermal, and aggregation properties. Analytical characteristics of oligolactide-based sensors and biosensors are discussed, with particular emphasis on the mechanism of signal generation and the contribution of modified materials to the selectivity and sensitivity of analysis.