Enviar artigo por via de e-mail Asymmetric Michael reaction between aldehydes and nitroalkanes promoted by pyrrolidine-containing C2-symmetric organocatalysts
- Autores: Bykova K.A.1,2, Kostenko A.A.1, Kucherenko A.S.1, Zlotin S.G.1
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Afiliações:
- N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
- Dmitry Mendeleev University of Chemical Technology of Russia
- Edição: Volume 68, Nº 7 (2019)
- Páginas: 1402-1406
- Seção: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/243429
- DOI: https://doi.org/10.1007/s11172-019-2568-2
- ID: 243429
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Resumo
Bifunctional C2-symmetric organocatalysts derived from chiral 1,2-diaminoethanes and (S)-2-aminomethylpyrrolidine were fi rst used for promoting the asymmetric Michael addition of aliphatic aldehydes to nitroalkenes. The synthesized enantioenriched (up to 82% ee) products can be transformed into various biologically active γ-aminobutyric acid derivatives.
Sobre autores
K. Bykova
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences; Dmitry Mendeleev University of Chemical Technology of Russia
Email: bykova_ksyusha@mail.ru
Rússia, 47 Leninsky prosp., Moscow, 119991; 9 Miusskaya pl., Moscow, 125047
A. Kostenko
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Autor responsável pela correspondência
Email: bykova_ksyusha@mail.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
A. Kucherenko
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: bykova_ksyusha@mail.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
S. Zlotin
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: bykova_ksyusha@mail.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
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