Bisdiamidophosphite with a bisoxazoline moiety in palladium-catalyzed enantioselective allylation
- Autores: Gavrilov K.N.1, Zheglov S.V.1, Gavrilov V.K.1, Firsin I.D.1, Maksimova M.G.1
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Afiliações:
- S. A. Yesenin Ryazan State University
- Edição: Volume 68, Nº 7 (2019)
- Páginas: 1376-1379
- Seção: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/243425
- DOI: https://doi.org/10.1007/s11172-019-2564-6
- ID: 243425
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Resumo
A bisdiamidophosphite ligand with stereogenic phosphorus atoms as a part of 1,3,2-diaza-phospholidine rings and a bisoxazoline backbone was synthesized and studied in the Pd-catalyzed asymmetric allylic substitution. The use of this ligand provided up to 93% ee in the alkylation of (E)-1,3-diphenylallyl acetate with dimethyl malonate and up to 77% ee in the amination with pyrrolidine at quantitative conversion of the starting substrate.
Sobre autores
K. Gavrilov
S. A. Yesenin Ryazan State University
Autor responsável pela correspondência
Email: k.gavrilov@rsu.edu.ru
Rússia, 46 ul. Svobody, Ryazan, 390000
S. Zheglov
S. A. Yesenin Ryazan State University
Email: k.gavrilov@rsu.edu.ru
Rússia, 46 ul. Svobody, Ryazan, 390000
V. Gavrilov
S. A. Yesenin Ryazan State University
Email: k.gavrilov@rsu.edu.ru
Rússia, 46 ul. Svobody, Ryazan, 390000
I. Firsin
S. A. Yesenin Ryazan State University
Email: k.gavrilov@rsu.edu.ru
Rússia, 46 ul. Svobody, Ryazan, 390000
M. Maksimova
S. A. Yesenin Ryazan State University
Email: k.gavrilov@rsu.edu.ru
Rússia, 46 ul. Svobody, Ryazan, 390000
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