Lipase enzymatic microreactor in polysaccharide hydrogel: structure and properties

Abstract

An enzymatic microreactor was designed on the basis of sodium alginate hydrogel containing a lipolytic enzyme (Candida rugosa lipase) in the polymer matrix pores. The functional properties of lipase were characterized in polysaccharide hydrogel of different concentrations. The polysaccharide hydrogel matrix was shown to act as a microreactor, where the enzyme retains activity during numerous catalytic cycles and allows designing long-acting drug systems of enzymatic nature.