Email this article Efficient synthesis of 3,4-diarylpyrrole-2-carboxylates, the key fragments of natural antimitotic agents
- Authors: Silyanova E.A.1, Samet A.V.1, Semenov V.V.1
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Affiliations:
- N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
- Issue: Vol 67, No 12 (2018)
- Pages: 2316-2319
- Section: Brief Communications
- URL: https://journals.rcsi.science/1066-5285/article/view/243236
- DOI: https://doi.org/10.1007/s11172-018-2375-1
- ID: 243236
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Abstract
Barton-Zard reaction of nitrostilbenes with ethyl isocyanoacetate carried out in EtOH in the presence of K2CO3 allowed us to minimize the formation of side products and to obtain 3,4-diarylpyrrole-2-carboxylates in high yields.
About the authors
E. A. Silyanova
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Author for correspondence.
Email: cea93@mail.ru
Russian Federation, 47 Leninsky prosp., Moscow, 119991
A. V. Samet
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: cea93@mail.ru
Russian Federation, 47 Leninsky prosp., Moscow, 119991
V. V. Semenov
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: cea93@mail.ru
Russian Federation, 47 Leninsky prosp., Moscow, 119991
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