Email this article Mixed systems based on the cationic surfactant with a butyl carbamate fragment and nonionic surfactant Tween 80: Aggregation behavior and solubilization properties
- Authors: Mirgorodskaya A.B.1, Kushnazarova R.A.1, Shcherbakov A.Y.1, Lukashenko S.S.1, Zhukova N.A.1, Mamedov V.A.1,2, Zakharova L.Y.1,2, Sinyashin O.G.2
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Affiliations:
- A. E. Arbuzov Institute of Organic and Physical Chemistry – Subdivision of the Federal Reseach Center “Kazan Scientific Center of the Russian Academy of Sciences,”
- Kazan National Research Technological University
- Issue: Vol 67, No 11 (2018)
- Pages: 1992-1996
- Section: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/243157
- DOI: https://doi.org/10.1007/s11172-018-2319-9
- ID: 243157
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Abstract
Mixed micelles are formed in the binary compositions based on the cationic surfactant functionalized by the butyl carbamate fragment and nonionic surfactant Tween 80 in aqueous solutions. The aggregation parameters of the formed micelles (critical micelle concentration, size, and surface potential) depend on the component ratio in the system. The solubilization effect of individual and mixed micelles on the drugs of the heterocyclic series, indomethacin and 1-[5-(4-chlorophenyl)-3-phenylpyrrol-2-yl)]benzimidazol-2(3H)-one, was quantitatively characterized.
About the authors
A. B. Mirgorodskaya
A. E. Arbuzov Institute of Organic and Physical Chemistry – Subdivision of the Federal Reseach Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Author for correspondence.
Email: mirgoralla@mail.ru
Russian Federation, 8 ul. Akad. Arbuzova, Kazan, 420088
R. A. Kushnazarova
A. E. Arbuzov Institute of Organic and Physical Chemistry – Subdivision of the Federal Reseach Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: mirgoralla@mail.ru
Russian Federation, 8 ul. Akad. Arbuzova, Kazan, 420088
A. Yu. Shcherbakov
A. E. Arbuzov Institute of Organic and Physical Chemistry – Subdivision of the Federal Reseach Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: mirgoralla@mail.ru
Russian Federation, 8 ul. Akad. Arbuzova, Kazan, 420088
S. S. Lukashenko
A. E. Arbuzov Institute of Organic and Physical Chemistry – Subdivision of the Federal Reseach Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: mirgoralla@mail.ru
Russian Federation, 8 ul. Akad. Arbuzova, Kazan, 420088
N. A. Zhukova
A. E. Arbuzov Institute of Organic and Physical Chemistry – Subdivision of the Federal Reseach Center “Kazan Scientific Center of the Russian Academy of Sciences,”
Email: mirgoralla@mail.ru
Russian Federation, 8 ul. Akad. Arbuzova, Kazan, 420088
V. A. Mamedov
A. E. Arbuzov Institute of Organic and Physical Chemistry – Subdivision of the Federal Reseach Center “Kazan Scientific Center of the Russian Academy of Sciences,”; Kazan National Research Technological University
Email: mirgoralla@mail.ru
Russian Federation, 8 ul. Akad. Arbuzova, Kazan, 420088; 68 ul. K. Marksa, Kazan, 420015
L. Ya. Zakharova
A. E. Arbuzov Institute of Organic and Physical Chemistry – Subdivision of the Federal Reseach Center “Kazan Scientific Center of the Russian Academy of Sciences,”; Kazan National Research Technological University
Email: mirgoralla@mail.ru
Russian Federation, 8 ul. Akad. Arbuzova, Kazan, 420088; 68 ul. K. Marksa, Kazan, 420015
O. G. Sinyashin
Kazan National Research Technological University
Email: mirgoralla@mail.ru
Russian Federation, 68 ul. K. Marksa, Kazan, 420015
