Email this article 2-Allyloxy/propargyloxypyridines: synthesis, structure, and biological activity
- Authors: Babaev E.V.1, Koval Y.I.1, Rybakov V.B.1, Paronikyan E.G.2, Stepanyan G.M.2, Paronikyan R.G.2, Dashyan S.S.2, Rzhevskii S.A.1, Shadrin I.A.1
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Affiliations:
- Department of Chemistry, M. V. Lomonosov Moscow State University
- A. L. Mnjoyan Institute of Fine Organic Chemistry of Scientific-Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
- Issue: Vol 67, No 2 (2018)
- Pages: 313-320
- Section: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/242178
- DOI: https://doi.org/10.1007/s11172-018-2076-9
- ID: 242178
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Abstract
The alkylation (allylation and propargylation) of 3-cyano-6-dialkylamino-2-pyridones containing a d-annulated ring occurs at the oxygen atom. The structures of the starting compounds and their alkylation products were determined by X-ray diffraction. The neurotropic and antimicrobial activity of alkylation products was examined.
About the authors
E. V. Babaev
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: babaev@org.chem.msu.ru
Russian Federation, 1, Build. 3, Leninskie Gory, Moscow, 119992
Y. I. Koval
Department of Chemistry, M. V. Lomonosov Moscow State University
Author for correspondence.
Email: babaev@org.chem.msu.ru
Russian Federation, 1, Build. 3, Leninskie Gory, Moscow, 119992
V. B. Rybakov
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: babaev@org.chem.msu.ru
Russian Federation, 1, Build. 3, Leninskie Gory, Moscow, 119992
E. G. Paronikyan
A. L. Mnjoyan Institute of Fine Organic Chemistry of Scientific-Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: babaev@org.chem.msu.ru
Armenia, 26 Azatutyan aven., Yerevan 26, 0014
G. M. Stepanyan
A. L. Mnjoyan Institute of Fine Organic Chemistry of Scientific-Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: babaev@org.chem.msu.ru
Armenia, 26 Azatutyan aven., Yerevan 26, 0014
R. G. Paronikyan
A. L. Mnjoyan Institute of Fine Organic Chemistry of Scientific-Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: babaev@org.chem.msu.ru
Armenia, 26 Azatutyan aven., Yerevan 26, 0014
Sh. Sh. Dashyan
A. L. Mnjoyan Institute of Fine Organic Chemistry of Scientific-Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: babaev@org.chem.msu.ru
Armenia, 26 Azatutyan aven., Yerevan 26, 0014
S. A. Rzhevskii
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: babaev@org.chem.msu.ru
Russian Federation, 1, Build. 3, Leninskie Gory, Moscow, 119992
I. A. Shadrin
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: babaev@org.chem.msu.ru
Russian Federation, 1, Build. 3, Leninskie Gory, Moscow, 119992
