Electrosynthesis of biologically active dicycloalkyl di- and trisulfides involving an H2S—S8 redox system
- Authors: Berberova N.T.1, Smolyaninov I.V.1,2, Shinkar E.V.1, Kuzmin V.V.1, Sediki D.B.1, Shevtsova A.V.1
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Affiliations:
- Astrakhan State Technical University
- Southern Scientific Center, Russian Academy of Sciences
- Issue: Vol 67, No 1 (2018)
- Pages: 108-113
- Section: Article
- URL: https://journals.rcsi.science/1066-5285/article/view/241945
- DOI: https://doi.org/10.1007/s11172-018-2044-4
- ID: 241945
Cite item
Abstract
Biologically active dicycloalkyl di- and trisulfides were prepared by the reactions of cycloalkanes C5—C7 with H2S and S8 under the anodic (cathodic) activation of hydrogen sulfide. In dichloromethane, the electrochemical activation of H2S in the presence of sulfur can generate sulfur-centered radical intermediates that react with cycloalkanes at room temperature. The current yield of di- and trisulfides depends on the method of redox activation of hydrogen sulfide, the concentration of sulfur, and the time of electrosynthesis. The anodic activation of hydrogen sulfide in the synthesis of dicycloalkyl di- and trisulfides in an excess S8 is more efficient than the cathodic activation. In the series of cycloalkanes C5—C7, the highest yield of sulfur-containing products is observed for cycloheptane.
About the authors
N. T. Berberova
Astrakhan State Technical University
Author for correspondence.
Email: nberberova@gmail.com
Russian Federation, 16 ul. Tatishcheva, Russia, Astrakhan, 414056
I. V. Smolyaninov
Astrakhan State Technical University; Southern Scientific Center, Russian Academy of Sciences
Email: nberberova@gmail.com
Russian Federation, 16 ul. Tatishcheva, Russia, Astrakhan, 414056; 41 prosp. Chekhova, Rostov-on-Don, 344006
E. V. Shinkar
Astrakhan State Technical University
Email: nberberova@gmail.com
Russian Federation, 16 ul. Tatishcheva, Russia, Astrakhan, 414056
V. V. Kuzmin
Astrakhan State Technical University
Email: nberberova@gmail.com
Russian Federation, 16 ul. Tatishcheva, Russia, Astrakhan, 414056
D. B. Sediki
Astrakhan State Technical University
Email: nberberova@gmail.com
Russian Federation, 16 ul. Tatishcheva, Russia, Astrakhan, 414056
A. V. Shevtsova
Astrakhan State Technical University
Email: nberberova@gmail.com
Russian Federation, 16 ul. Tatishcheva, Russia, Astrakhan, 414056